Treatment of Monolateral Legg-Calvé-Perthes Disease with Autologous Bone Marrow Mononuclear Cells in 32 Dogs

Osteochondritis dissecans following Legg-Calvé-Perthes' disease.

Implantation of autologous bone marrow mononuclear cells as a minimal invasive therapy of Legg-Calve-Perthes disease in the dog

Objective: The cell therapy is at present considered a novel solution for the regeneration and also for the treatment of some disease of many tissues including bone and other mesenchymal derived tissues. The Legg-Calvè-Perthes (LCP) syndrome is a degenerative disease of the hip joint which is characterized by idiopatic avascular osteonecrosis of femoral head. This disease typically occurs in yo...

Editorial LEGG - CALVÉ - PERTHES DISEASE : 100 YEARS

Legg-Calvé-Perthes disease (LCPD) started to be studied 100 years ago (1910), thanks to the advent of the possibility of conducting clinical studies by means of radiographic images (1895). However, many questions remain open, both in relation to the etiology of this orthopedic condition and in relation to which therapeutic measures are valid. Thus, great controversy has been generated. In 1910,...

Legg-Calvé-Perthes disease: current concepts.

Perthes is a serious but self-limited disorder. If it is a self limiting disease, then why one should think of treating it. The aim of treatment is to prevent femoral head deformity and subsequent osteoarthrosis. There is still no clear guideline for the management of Perthes disease. This is because of the controversies in all most all the aspects of the disease; etiology, classification, natu...

Legg-Calvé-Perthes disease in a child with osteopetrosis

Osteopetrosis is a rare inherited disorder of bone causing increased bone density. Legg-Calvé-Perthes disease (LCPD), by contrast, is a more common idiopathic condition leading to variable avascular necrosis of the immature femoral head. We present a case of a 5-year-old boy presenting with these co-morbidities. We have found only one previous reference suggesting these two conditions can coexi...